Centella asiatica (also known as Gotu Kola) is an important medicinal and edible plant. Its key active compounds — primarily triterpenoids (such as asiaticoside, madecassoside, asiatic acid, and madecassic acid) along with flavonoids and polyphenols — are in high demand in modern pharmaceuticals, nutraceuticals, and cosmetics. These applications place strict requirements on the fineness, uniformity, and preservation of bioactivity of the powder.
Traditional grinding methods (such as hammer mills, blade mills, ordinary impact mills, or ball mills) often encounter significant limitations when processing Centella asiatica, while máy nghiền khí nén (especially fluidized-bed opposed jet mills or flat jet mills) has become the mainstream choice for high-end superfine grinding of this material. Below we systematically explain: why Centella asiatica particularly requires phay bằng tia khí, and its real advantages over traditional mechanical grinding.
Why Is Máy nghiền khí nén Especially Suitable (or Necessary) for Centella Asiatica?
Centella asiatica has material characteristics that make traditional methods inefficient and cause quality loss:
- High content of volatile and heat-sensitive components Volatile oils, phenolic acids, polysaccharides, and other constituents in Centella asiatica are highly sensitive to temperature. Decomposition or volatilization becomes noticeable above 60–80°C.
- High fiber content and tough texture The leaves and aerial parts contain substantial cellulose and hemicellulose. Traditional mechanical shearing tends to cause “slipping,” fiber entanglement, and incomplete grinding, often resulting in long fiber clumps.
- Active ingredients mainly concentrated in surface cells Triterpene saponins are primarily located in the epidermis and parenchyma cells. Excessive mechanical force can damage cell structures, leading to entrapment or oxidation of active compounds.
- End products demand extremely high fineness and narrow kích thước hạt phân bổ
- Oral solid preparations (granules, capsules): typically require D90 ≤ 20–30 μm
- Cosmetic-grade applications: often need D50 ≤ 5–10 μm, or even sub-micron levels
- Transdermal formulations: finer particles significantly improve stratum corneum penetration
Traditional mechanical grinding struggles to simultaneously meet the four critical requirements of low temperature + ultrafine size + narrow distribution + low contamination. Air jet milling excels precisely in these pain points.
Core Advantages of Air Jet Mill Compared to Traditional Grinding
| Aspect | Traditional Mechanical Grinding (Hammer, Blade, máy nghiền bi, etc.) | Air Jet Milling (especially Fluidized-Bed / Opposed Jet Mill) | Practical Significance for Centella Asiatica Processing |
|---|---|---|---|
| Grinding Temperature | Usually rises 40–100°C or more | Almost no temperature rise (can even be cooled below room temperature) | Maximizes retention of volatile oils, polyphenols, and triterpene glycosides |
| Độ tinh tế cuối cùng | Generally 100–325 mesh (150–45 μm), difficult to go finer | Easily achieves 1–20 μm, D50 as low as 2–8 μm | Dramatically improves bioavailability and transdermal efficiency |
| Phân bố kích thước hạt | Wide distribution (multi-modal, uneven) | Extremely narrow (single peak, highly uniform) | Easier quality control, minimal batch-to-batch variation |
| Cơ chế nghiền | Mechanical shear + impact + abrasion | Particle-to-particle collision (almost no media, no shear) | More complete cell wall rupture, minimal fiber tangling |
| Metal/Media Contamination | Present (from hammers, balls, liners) | Virtually none (no moving parts, no grinding media) | Ideal for premium cosmetics and export-grade herbal pieces |
| Oxidation & Enzymatic Browning | More severe (long air exposure + heat) | Very minimal (closed system, short processing time) | Final powder retains greener color and fresher aroma |
| Suitability for Heat-Sensitive / Sugar-Containing Materials | Poor | Xuất sắc | High retention of polysaccharides and volatile components |
| Công suất (kg/h) | Moderate | Medium to high (optimized models reach high throughput) | Suitable for industrial-scale production |
| Cleaning & Batch Changeover | More difficult (many dead corners) | Relatively easy (simple structure) | Reduced risk of cross-contamination |
Real-World Production Data Comparison (Industry Reference Values)
- Conventional grinding of Centella asiatica → 80–120 mesh, asiaticoside retention ≈ 82–88%, powder tends to be dark brownish
- Air jet milled superfine powder → 400–2000 mesh (D50 ≈ 3–12 μm), asiaticoside retention ≥ 94–98%, powder shows vibrant green color and fresh aroma
In particular, for cosmetic-grade Centella asiatica powder, air jet milling has become almost standard because it uniquely achieves:
- Sufficient fineness (for better skin penetration)
- Virtually no thermal degradation (high active retention)
- Extremely low microbial and heavy metal contamination risk (no media)
Phần kết luận: Why Air Jet Mill Is the Preferred Choice for High-End Centella Asiatica Powder
Centella asiatica is most vulnerable to “heat + contamination + excessive mechanical damage,” and air jet milling counters these three major threats using a “cold + pure particle collision + closed ultrafine” approach.
For ordinary tea blends, feed-grade, or rough processing, traditional mechanical grinding remains the most cost-effective option. However, once the product targets mid-to-high-end nutraceuticals, functional cosmetics, export-grade herbal decoction pieces, or transdermal preparations, air jet milling shifts from “optional” to “essentially required.”
Looking ahead, as nano-traditional Chinese medicine and advanced transdermal delivery systems continue to develop, the target particle size for Centella asiatica powder is likely to move toward 1–5 μm or even sub-micron levels. Air jet mill — especially upgraded models using inert gas or cryogenic airflow — will remain one of the most reliable industrial methods to achieve this goal.
Cảm ơn bạn đã đọc. Tôi hy vọng bài viết của tôi hữu ích. Vui lòng để lại bình luận bên dưới. Bạn cũng có thể liên hệ với bộ phận chăm sóc khách hàng trực tuyến của Zelda nếu có bất kỳ thắc mắc nào khác.
— Đăng bởi Emily Chen